First, setup a main (eth1 hereafter) IP address via
/etc/network/interfaces, such as
auto lo
iface lo inet loopback
auto eth1
iface eth1 inet static
address 192.168.99.2
netmask 255.255.255.0
gateway 192.168.99.1
And change /etc/resolv.conf, such as
nameserver 202.112.80.106
At last add alias to /etc/network/interfaces, such as
auto eth1:0
iface eth1:0 inet static
address 210.31.77.2
netmask 255.255.255.0
gateway 210.31.77.1
auto eth1:1
iface eth1:1 inet static
address 124.205.19.108
netmask 255.255.255.0
gateway 124.205.19.105
resolve.conf的信息会被network-manager 冲掉。